The 1950E series are likely to be more valuable as there were less of these printed compared to previous series. They are worth between $50-$75 in uncirculated condition with some more sought after examples selling at auction for upwards of $3000. The 1950 20 Dollar Bill was printed in six different series which ran from November 1950 though July 1966.
1950 $20 Bill How Much Is The 1950 20 Dollar Bill Worth?.